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Our Guiding Principles
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Ingredients Directory
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Type of Ingredient
NAD⁺ Precursor
Purpose
Explain what this ingredient does, in your own words.
Supporting Study
You Y, Gao Y, Wang H, Li J, Zhang X, Zhu Z, Liu N. "Subacute Toxicity Study of Nicotinamide Mononucleotide via Oral Administration." Frontiers in Pharmacology, 2020.
Type of Ingredient
Coenzyme
Purpose
Explain what this ingredient does, in your own words.
Supporting Studies
Loftus JP, Baxter TL, et al. "A randomized, double-blind, placebo-controlled clinical trial of a senolytic and NAD precursor in senior dogs." Scientific Reports, 2024.
Shen H, Ieronimakis N, et al. "Nicotinamide supplementation improves muscle pathology in a canine model of Duchenne muscular dystrophy through enhanced NAD⁺ metabolism." NPJ Regenerative Medicine, 2023.
Type of Ingredient
Mitochondrial Cofactor / Antioxidant
Purpose
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Supporting Studies
Druzhaeva N, Kovacevic A, et al. "Randomized, double-blinded, controlled trial of the effects of coenzyme Q10 supplementation on plasma coenzyme Q10 concentration in dogs with myxomatous mitral valve disease." American Journal of Veterinary Research, 2021.
Druzhaeva N, Kovacevic A, et al. "Effects of Coenzyme Q10 Supplementation on Oxidative Stress Markers, Inflammatory Markers, Lymphocyte Subpopulations and Clinical Status in Dogs with Myxomatous Mitral Valve Disease." Antioxidants, 2022.
Kovacevic A, Druzhaeva N, et al. "Myocardial Coenzyme Q10 concentrations in dogs with naturally occurring myxomatous mitral valve disease." Antioxidants, 2021.
Type of Ingredient
Polyphenol
Purpose
Explain what this ingredient does, in your own words.
Supporting Studies
Mathew LM, Woode RA, Axiak-Bechtel SM, Amorim JR, DeClue AE. "Resveratrol Administration Increases Phagocytosis, Decreases Oxidative Burst, and Promotes Pro-Inflammatory Cytokine Production in Healthy Dogs." Veterinary Immunology and Immunopathology, 2018.
Bian Z, Li Z, Chang H, Luo J, Jian S, Zhang J, Lin P, Deng B, Deng J, Zhang L. "Resveratrol Ameliorates Chronic Stress in Kennel Dogs and Mice by Regulating Gut Microbiome and Metabolome Related to Tryptophan Metabolism." Antioxidants, 2025.
Johnson WD, Morrissey RL, Usborne AL, Kapetanovic I, Crowell JA, Muzzio M, McCormick DL. "Subchronic oral toxicity and cardiovascular safety pharmacology studies of resveratrol, a naturally occurring polyphenol with cancer preventive activity." Food and Chemical Toxicology, 2011.
Our Process
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